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Modern Microscopy

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16.08.2022
17:33 Phys.org New cryo-EM images shed light on Wnt signaling

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported in Nature, shed light on the mechanisms behind this activity and could eventually lead to new drugs to treat various malignancies.

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12.08.2022
21:33 Phys.org Optical microscope strategy allows observers to check electrons moving inside gold

A team led by DGIST professor Seo Dae-ha has developed an experimental strategy to control and observe the chemical reaction of a single nanocatalyst using an optical microscope. The work is expected to contribute to catalyst design based on accurate understanding of the photocatalytic reaction through an analysis method that helps understanding the electron excitation phenomenon and transition path.

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31.07.2022
10:13 Technology.org Researchers Take First-Ever Cryo-EM Images of Nitrogenase in Action

Previously, it has been impossible to capture high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen

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29.07.2022
00:10 ScienceDaily.com Researchers take first-ever cryo-EM images of nitrogenase in action

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action. Now researchers report near-atomic-resolution snapshots of nitrogenase during catalysis using cryogenic electron microscopy.

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28.07.2022
22:13 Phys.org Researchers take first-ever cryo-EM images of nitrogenase in action

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action. Now, for the first time, researchers at the University of California San Diego report near-atomic-resolution snapshots of nitrogenase during catalysis using cryogenic electron microscopy (cryoEM). The results were published in the journal Science.

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27.07.2022
21:00 Nature.Com Tracking single adatoms in liquid in a Transmission Electron Microscope

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

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26.07.2022
20:33 Phys.org Researchers develop novel 3D atomic force microscopy probes

A team of researchers from NYU Abu Dhabi's Advanced Microfluidics and Microdevices Laboratory (AMMLab) have developed new kind of Atomic Force Microscopy (AFM) probes in true three-dimensional shapes they call 3DTIPs. AFM technology allows scientists to observe, measure, and manipulate samples and micro and nanoscale entities with unprecedented precision. The new 3DTIPs, which are manufactured using a single-step 3D printing process, can be utilized for a wider variety of applications—and potential observations and discoveries—than standard, more limited silicon-based probes that are considered state-of-the-art in our current time.

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25.07.2022
16:53 Phys.org Defect dynamics at the buried interface revealed by photoemission electron microscopy

In recent years, LaAlO3/SrTiO3 interface is found to be an ideal host for two-dimensional electron gas (2DEG). Such heterostructures have attracted extensive interests in recent years due to their various fascinating properties such as high electron mobility, superconductivity, and tunable spin-orbit coupling effect.

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20.07.2022
20:20 Nature.Com Cryo-EM structure of an active bacterial TIR–STING filament complex

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12:33 AzoNano.com New Cypher L Atomic Force Microscope Provides Higher Resolution and a Simpler User Experience for Core Nanoscience Research Fields

Oxford Instruments Asylum Research today announced the launch of the new Cypher L atomic force microscope (AFM). Based on the acclaimed high-performance Cypher AFM platform, the Cypher L is...

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13.07.2022
19:30 Nature.Com Atomic imaging of zeolite-confined single molecules by electron microscopy

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12.07.2022
11:23 Phys.org First cryo-EM structures of angiotensin-converting enzyme pave the way for better drugs to treat heart disease

The first full-length structures of the human angiotensin-converting enzyme (ACE) have been determined by researchers from the University of Cape Town (UCT) using cryo-electron microscopy (cryo-EM). ACE is a blood pressure-regulating protein that is critical for heart health.

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29.06.2022
18:13 Phys.org Assigning moving features in high-speed atomic force microscopy

Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.

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10:53 Nanowerk.com Assigning moving features in high-speed atomic force microscopy

How to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.

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27.06.2022
19:30 Aps.org Editors' Suggestions Momentum microscopy of Pb-intercalated graphene on SiC: Charge neutrality and electronic structure of interfacial Pb

Author(s): Bharti Matta, Philipp Rosenzweig, Olaf Bolkenbaas, Kathrin Küster, and Ulrich StarkeThe authors show the band structure formation of a two-dimensional Pb crystal intercalated below charge-neutral quasi-freestanding graphene on SiC [Phys. Rev. Research 4, 023250] Published Mon Jun 27, 2022

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22.06.2022
19:00 Nature.Com Cryo-EM structure of a type IV secretion system

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14.06.2022
18:23 AzoNano.com 3D Atomic Force Microscopy Offers Insights into Chitin Nanocrystals

Chitin is a renewable biopolymer that is abundantly available in nature. Despite its importance as a basic building block in various biological materials, its surface crystalline structure remains...

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10.06.2022
21:50 Nature.Com Nanoscale imaging of phonon dynamics by electron microscopy

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09.06.2022
21:03 Phys.org With cryo-EM, scientists determine structure of key factor in RNA quality control

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

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07.06.2022
17:13 Phys.org Investigating electrons with a traditional scanning microscope

Physicists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have designed a framework that allows scientists to observe interactions between light and electrons using a traditional scanning electron microscope. The procedure is considerably cheaper than the technology that has been used to date, and also enables a wider range of experiments. The researchers have published their findings in the journal Physical Review Letters.

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12:43 Nanowerk.com Investigating electrons with a traditional scanning microscope

Physicists have designed a framework that allows scientists to observe interactions between light and electrons using a traditional scanning electron microscope. The procedure is considerably cheaper than the technology that has been used to date, and also enables a wider range of experiments.

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06.06.2022
17:30 Aps.org Editors' Suggestions Quantum-Coherent Light-Electron Interaction in a Scanning Electron Microscope

Author(s): R. Shiloh, T. Chlouba, and P. HommelhoffScanning electron microscopes enter the electron quantum optics ring with the capability to engineer electron quantum states using lasers. [Phys. Rev. Lett. 128, 235301] Published Mon Jun 06, 2022

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02.06.2022
22:53 Phys.org Using advanced microscopy to nanoengineer new materials for computing and electronics

Researchers at Oak Ridge National Laboratory and Korea's Sungkyunkwan University are using advanced microscopy to nanoengineer promising materials for computing and electronics in a beyond-Moore era.

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27.05.2022
16:40 ScienceDaily.com Cryogenic electron microscopy reveals drug targets against common fungus

Scientists have used single-particle cryogenic electron microscopy to determine the structure of the ribosome of Candida albicans. Their results reveal a potential target for new drugs.

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26.05.2022
18:33 AzoNano.com Scientists Monitor Crystallization of Nickel Using Liquid-Phase Electron Microscopy

A lack of knowledge of how nickel crystallizes into a solid has hampered its prospective application in new nanomaterials and as a low-cost catalyst in chemical reactions that are performed...

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25.05.2022
21:43 Phys.org Cryogenic electron microscopy reveals drug targets against common fungus

Most people carry the fungus Candida albicans on their bodies without it causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat. Few antimicrobials are effective, and drug resistance is increasing. An international group of scientists, including Albert Guskov, associate professor at the University of Groningen, have used single-particle cryogenic electron microscopy to determine the structure of the fungal ribosome. Their results, which were published in Science Advances on 25 May, reveal a potential target for new drugs.

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17:03 AzoNano.com Using Cryo-Electron Microscopy to Analyze Protein–Nanoparticle Structures

The composition of protein-nanoparticle complexes can be studied utilizing technologies that enable the investigation of biological molecules' interactions with inorganic compounds. A recent study...

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30.04.2022
10:03 Technology.org See how quantum ‘weirdness’ is improving electron microscopes

Quantum weirdness is opening new doors for electron microscopes, powerful tools used for high-resolution imaging. Two new advances

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28.04.2022
14:03 Phys.org How quantum weirdness is improving electron microscopes

Quantum weirdness is opening new doors for electron microscopes, powerful tools used for high-resolution imaging.

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27.04.2022
19:02 Nature.Com USP14-regulated allostery of the human proteasome by time-resolved cryo-EM

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11.04.2022
20:10 ScienceDaily.com Electron lens formed by light: A new method for atomic-resolution electron microscopes

Researchers have proposed a new method to form an electron lens that will help reduce installation costs for electron microscopes with atomic resolution, proliferating their use. Instead of the electrostatic and magnetic fields employed in conventional electron lenses, they utilized a light field electron-lens.

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17:33 Phys.org A new method to form a lens for atomic-resolution electron microscopes

Electron microscopy enables researchers to visualize tiny objects such as viruses, the fine structures of semiconductor devices, and even atoms arranged on a material surface. Focusing down the electron beam to the size of an atom is vital for achieving such high spatial resolution. However, when the electron beam passes through an electrostatic or magnetic lens, the rays of electrons exhibit different focal positions depending on the focusing angle and the beam spreads out at the focus. Correcting this "spherical aberration" is costly and complex, meaning that only a select few scientists and companies possess electron microscopes with atomic resolution.

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10:23 Nanowerk.com Electron lens formed by light: A new method for atomic-resolution electron microscopes

Researchers propose a new method to form an electron lens that will help reduce installation costs for electron microscopes with atomic resolution, proliferating their use. Instead of the electrostatic and magnetic fields employed in conventional electron lenses, they utilized a light field electron-lens.

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07.04.2022
20:50 ScienceDaily.com Cryo-EM imaging of STING protein reveals new binding pocket

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, scientists report. The findings could lead to new ways of manipulating STING to prompt stronger immune responses or stem its action in autoimmune diseases.

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31.03.2022
19:50 ScienceDaily.com A scaffold with a twist: Cryo-EM reveals the building blocks of poxvirus

Researchers have revealed how poxviruses build their scaffold - a temporary protein coat that forms and disappears as the virus matures.

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21.03.2022
21:16 ScienceDaily.com Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem -- a failsafe that is critical to maintaining health and staving off disease. Now, scientists have for the first time revealed how a key piece of this repair process -- appropriately called the 911 DNA checkpoint clamp -- is recruited to the site of DNA damage. The findings illuminate new insights into the way cells ensure genetic instructions are properly passed from one generation of cells to the next.

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20:26 Phys.org Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

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16:58 Phys.org Using electron microscopy and automatic atom-tracking to learn more about grain boundaries in metals during deformation

A team of researchers affiliated with multiple institutions in China and the U.S. has found that it is possible to track the sliding of grain boundaries in some metals at the atomic scale using an electron microscope and an automatic atom tracker. In their paper published in the journal Science, the group describes their study of platinum using their new technique and the discovery they made in doing so.

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12.03.2022
17:25 Technology.org Crystallography, cryo-EM and AlphaFold: a perfect trio sheds light on key human antibacterial proteins

A team led by Karolinska Institutet has combined Artificial Intelligence (AI) with structural biology to gain insights into

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11.03.2022
17:00 Phys.org Crystallography, cryo-EM and AlphaFold shed light on key human antibacterial proteins

A team led by Karolinska Institutet has combined Artificial Intelligence (AI) with structural biology to gain insights into two similar proteins that prevent bacterial infection in the urinary tract and the gastrointestinal system. Their results are published in Nature Structural & Molecular Biology.

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24.02.2022
21:17 ScienceDaily.com Visualization of the origin of magnetic forces by atomic resolution electron microscopy

Scientists have observed atomic magnetic fields, the origin of magnetic forces, for the first time using an innovative Magnetic-field-free Atomic-Resolution STEM they developed.

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17:09 Phys.org Visualization of the origin of magnetic forces by atomic resolution electron microscopy

The joint development team of Professor Shibata (the University of Tokyo), JEOL Ltd. and Monash University succeeded in directly observing an atomic magnetic field, the origin of magnets (magnetic force), for the first time in the world. The observation was conducted using the newly developed Magnetic-field-free Atomic-Resolution STEM (MARS). This team had already succeeded in observing the electric field inside atoms for the first time in 2012. However, since the magnetic fields in atoms are extremely weak compared with electric fields, the technology to observe the magnetic fields had been unexplored since the development of electron microscopes. This is an epoch-making achievement that will rewrite the history of microscope development.

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11:21 Nanowerk.com Visualization of the origin of magnetic forces by atomic resolution electron microscopy

Scientists have succeeded in directly observing an atomic magnetic field, the origin of magnets (magnetic force), for the first time.

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18.02.2022
04:17 ScienceDaily.com Monte Carlo simulations bring new focus to electron microscopy

A new method is using Monte Carlo simulations to extend the capabilities of transmission electron microscopy and answer fundamental questions in polymer science.

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17.02.2022
19:18 Nanowerk.com Monte Carlo simulations bring new focus to electron microscopy

New findings enable first direct, real-time images of radiation-sensitive soft nanomaterials in organic solvents.

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19:06 Phys.org Monte Carlo simulations bring new focus to electron microscopy

With highly specialized instruments, we can see materials on the nanoscale—but we can't see what many of them do. That limits researchers' ability to develop new therapeutics and new technologies that take advantage of their unusual properties.

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14.02.2022
15:03 Phys.org Solving the ice problem in cryo-electron microscopy

Cryo-EM requires protein samples to be frozen before they are imaged using an electron microscope. This revolutionary technique and its application to structural biology was the focus of the Nobel Prize for Chemistry in 2017 and has contributed to a wave of new structural information for proteins that were difficult or impossible to prepare for X-ray crystallography. As cryo-EM became more popular, new methods and tools arose to improve the technique and make it more efficient. Now, many people are working on the way that samples are prepared so that this is easier to get high resolution structural information from each experiment. Once samples are prepared, there are a number of automated tools that have been developed for picking the frozen particles to be processed. It was while investigating these tools that Ph.D. student Mateusz Olek and his supervisor Peijun Zhang with help from Yuriy Chaban and Donovan Webb, uncovered an unusual problem. Their findings have been published in the

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11.02.2022
15:34 Phys.org Molecular cage gives cryo-EM researchers new insights into a cancer protein

Acute myeloid leukemia (AML), the American Cancer Institute estimates, will affect more than 20,000 Americans this year and kill more than 11,000 of them. Many of those who are treated with intensive chemotherapy or stem cell transplantation will have side effects, including infections, hair loss and vomiting, in addition to long term complications.

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01.02.2022
19:24 Phys.org Scientists invent world's first advanced laser microscope to study chiral molecules

Scientists from Durham University's Chemistry Department have developed the world's first laser scanning confocal microscope that can harness Circularly Polarized Light (CPL) to differentiate left and right-handed molecules, also known as chiral molecules.   

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15:48 AzoNano.com Argonne’s Ultrafast Electron Microscope Reveals Small Details with Potentially Big Impacts

A unique instrument at Argonne's Center for Nanoscale Materials combines a modified transmission electron microscope with an ultrafast laser system to reveal small details with potentially big...

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20.01.2022
16:14 ScienceDaily.com New electron microscopy technique could shortcut the development of vaccines and monoclonal antibody therapies

A new method identifies specific antibodies in immune responses to vaccination or infection in fraction of time needed for traditional approach.

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19.01.2022
17:54 AzoNano.com Nanosurf Introduces a Cutting-Edge Tip-Scanning Atomic Force Microscope

Nanosurf, a global provider of scanning probe microscopes, has launched the DriveAFM — a high-performance tip-scanning AFM that incorporates innovative technologies. The DriveAFM was is designed...

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06.01.2022
15:36 Phys.org Ultrafast amplitude detector for use in high-speed atomic force microscopy

To improve our understanding of biomolecular processes happening within cells, techniques for visualizing and recording them are of key importance. High-speed atomic-force microscopy (HS-AFM) has become an important technique for the real-time observation of biological processes on the sub-molecular spatial scale and with sub-second time resolution. Still, a higher video frame rate is required for recording many important processes, such as ion transport motion or signaling mechanisms within membranes. Now, Kenichi Umeda, Toshio Ando and Noriyuki Kodera from Kanazawa University and colleagues have designed an amplitude detector with ultrafast operation, the use of which in HS-AFM leads to a significantly improved temporal resolution.

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15:08 Nature.Com Author Correction: Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution

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10:43 Nanowerk.com Speeding up atomic force microscopy

Researchers designed an ultrafast amplitude detector for use in high-speed atomic force microscopy. The detector will enable the real-time recording of fast dynamical processes of biomolecules.

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27.12.2021
19:18 ScienceDaily.com Researchers use electron microscope to turn nanotube into tiny transistor

Researchers have used a unique tool inserted into an electron microscope to create a transistor that's 25,000 times smaller than the width of a human hair.

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24.12.2021
17:19 AzoNano.com Using Electron Microscope to Turn Nanotube into Tiny Transistor

An international team of researchers have used a unique tool inserted into an electron microscope to create a transistor that's 25,000 times smaller than the width of a human hair. The research,...

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10:54 Nanowerk.com Researchers use electron microscope to turn carbon nanotube into tiny transistor

In this work, researchers have shown it is possible to control the electronic properties of an individual carbon nanotube.

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23.12.2021
22:01 Phys.org Researchers use electron microscope to turn nanotube into tiny transistor

An international team of researchers have used a unique tool inserted into an electron microscope to create a transistor that's 25,000 times smaller than the width of a human hair.

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22.12.2021
20:21 Nanowerk.com Integrated photonics meets electron microscopy

In a new study, researchers have successfully demonstrated extremely efficient electron beam modulation using integrated photonic microresonators.

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19:42 Nature.Com Low-power light modifies electron microscopy

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19:32 Phys.org Integrated photonics meets electron microscopy

Scientists in Switzerland and Germany have achieved efficient electron-beam modulation using integrated photonics—circuits that guide light on a chip. The experiments could lead to entirely new quantum measurement schemes in electron microscopy.

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20.12.2021
09:28 Technology.org Artificial Intelligence magnifies the utility of electron microscopes

An AI framework enables Argonne scientists to improve a decades-old imaging technique.   With resolution 1,000 times greater than a light microscope,

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17.12.2021
11:25 Nanowerk.com Artificial Intelligence magnifies the utility of electron microscopes

An AI framework enables scientists to improve a decades-old imaging technique.

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01.12.2021
19:34 Phys.org Atomic force microscope measures adhesion energy of the coronavirus

A study by Department of Energy researchers detailed a potential method to detect the novel coronavirus on surfaces. Scientists from Pacific Northwest, Oak Ridge, Sandia and Ames national laboratories used an atomic force microscope to measure how easily particles of the virus's spike protein attached to surfaces, a property called adhesion energy.

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25.11.2021
18:22 AzoNano.com Lightwave-Driven Electron Microscope Probes Atom-Sized Graphene Nanoribbons

A team of researchers at Michigan State University have utilized lightwave-driven terahertz scanning tunneling microscopy and spectroscopy to probe 7-atom-wide armchair graphene nanoribbons (7-AGNRs)...

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16.11.2021
00:40 TechInvestorNews.com Powerful New Semiconductor Tool Introduced by Park Systems Combines Atomic Force Microscopy with Whi (Shannon Davis/Solid State Technology)

Shannon Davis / Solid State TechnologyPowerful New Semiconductor Tool Introduced by Park Systems Combines Atomic Force Microscopy with Whi - Park Systems, a manufacturer of Atomic Force Microscopes, presents Park NX-Hybrid WLI,the first fully integrated system that combines Atomic Force Microscopy (AFM) with White LightInterferometer (WLI) profilometry. Powerful New Semiconductor Tool Introduced by Park Systems Combines Atomic Force Microscopy with White Light Interferometry was posted by Shannon Davis on Semiconductor ...

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15.11.2021
14:43 AzoNano.com Powerful New Semiconductor Tool Introduced by Park Systems Combines Atomic Force Microscopy with White Light Interferometry

(Suwon, Korea  Nov. 15, 2021) Park Systems, world leading manufacturer of Atomic Force Microscopes announced the launch of Park NX-Hybrid WLI, the first fully integrated system that combines...

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11.11.2021
04:37 Nature.Com Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues

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03.11.2021
17:06 Nature.Com Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues

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06.10.2021
18:41 Nature.Com An open-access volume electron microscopy atlas of whole cells and tissues

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18:41 Nature.Com Whole-cell organelle segmentation in volume electron microscopy

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05.10.2021
18:58 Phys.org 3D structure of artificially designed protein nanoparticle TIP60 elucidated by cryo-electron microscopy

Nanoparticles and nanocages are attractive materials that may be applied in color agents, catalysts, and drug delivery. For real-world use, it is necessary to produce a large number of nanoparticles of uniform size and shape, but thus far, nanoparticle formation methods using metals have been widely researched, and the formation of nanoparticles with a certain shape and size have been realized. However, it is not easy to create a group of uniform nanoparticles with the same structure at the atomic level.

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17:40 Nanowerk.com 3D structure of artificially designed protein nanoparticle TIP60 elucidated by cryo-electron microscopy

The structure of a soccer-ball-shaped self-assembling supramolecular protein nanoparticle, TIP60, was elucidated by cryo-electron microscopy, with promising functionality modification potential for application in nanomaterials and nanobiotechnology.

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29.09.2021
19:16 Nature.Com Electron crystals come under the microscope

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21.09.2021
19:11 Phys.org New technique boosts cryo-electron microscopy clarity, safety

When scientists needed to visualize the structure of the spike protein, which coronaviruses use to infiltrate human cells, they turned to cryo-electron microscopy. One of the most powerful imaging tools in a researcher's arsenal, cryo-electron microscopy (cryo-EM) can visualize proteins, pathogens and sundry cell components almost down to their individual atoms.

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30.08.2021
15:38 WhatReallyHappened.com Scanning & Transmission Electron Microscopy Reveals Graphene Oxide, Parasite in CoV-19 Vaccines

What is in the vaccines? With use of electron and other kinds of microscopy, original research by Dr. Robert Young and his team, confirms what the La Quinta Columna researchers found—toxic nanometallic content, including graphene oxide, with cytotoxic and genotoxic effects as well as an identified parasite. “The Corona Effect and Spike Protein Effect The Endogenously Created “Corona Effect” and “Spike Protein” ARE Caused by Chemical and Radiation Poisoning from Reduced Graphene Oxide and Microwave Radiation!”

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29.08.2021
19:49 ScienceDaily.com Ultrafast electron microscopy leads to pivotal discovery

Researchers used ultrafast electron microscopy to study a nanoscale phenomenon that occurs in less than a few hundred quadrillionths of a second. Insights from the study could aid in the development of new sensors and quantum devices.

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27.08.2021
16:03 AzoNano.com Ultrafast Electron Microscope may Pave Way for the Development of Quantum Devices, Sensors

Ultrafast electron microscope opens up new avenues for the development of sensors and quantum devices. Everyone who has ever been to the Grand Canyon can relate to having strong feelings from being...

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09:03 Technology.org Ultrafast electron microscopy leads to pivotal discovery

Ultrafast electron microscope opens up new avenues for the development of sensors and quantum devices. Everyone who has

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00:30 Nanowerk.com Ultrafast electron microscopy leads to pivotal discovery

Scientists have discovered that nanoparticles of gold act unusually when close to the edge of a one-atom thick sheet of carbon, called graphene. This could have big implications for the development of new sensors and quantum devices.

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00:20 Phys.org Ultrafast electron microscopy leads to pivotal discovery

Everyone who has ever been to the Grand Canyon can relate to having strong feelings from being close to one of nature's edges. Similarly, scientists at the U.S. Department of Energy's (DOE) Argonne National Laboratory have discovered that nanoparticles of gold act unusually when close to the edge of a one-atom thick sheet of carbon, called graphene. This could have big implications for the development of new sensors and quantum devices.

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11.08.2021
18:37 Nature.Com Cryo-EM structures of full-length

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10.08.2021
01:43 ScienceDaily.com Overcoming the limitations of scanning electron microscopy with AI

A team develops a highly efficient super-resolution imaging based on deep learning.

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30.07.2021
19:35 Phys.org Electron microscopy in the age of automation

"Many of the greatest challenges of our time, from clean energy to environmental justice, require new approaches to the craft of scientific experimentation. This is exceedingly apparent in the field of electron microscopy. As researchers utilize this powerful window to peer into the atomic machinery behind today's technologies, they are increasingly inundated with data and constrained by traditional operating models. We must leverage artificial intelligence and machine learning in our scientific instruments if we are to unlock breakthrough discoveries."

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29.07.2021
01:13 ScienceDaily.com Scientists advance breast, ovarian cancer research with cryo-electron microscopy

Using advanced imaging technology, scientists have provided an unprecedented understanding of the BRCA1-BARD1 protein complex, which is often mutated in patients with breast or ovarian cancer. Their paper identifies aspects of how BRCA1-BARD1 functions, supporting future translational research, cancer prevention efforts and drug development.

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28.06.2021
14:54 AzoNano.com Park Systems Announces Park FX40, the Autonomous AFM with Built-in Intelligence - A Groundbreaking New Class of Atomic Force Microscope

Park Systems, the fastest growing manufacturer of Atomic Force Microscopes (AFM) just announced Park FX40, a groundbreaking autonomous atomic force microscope, infused with innovative robotics,...

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25.06.2021
14:52 Phys.org Time-resolved photoemission electron microscopy to probe electron dynamics of solid-state film OLEDs

Organic light-emitting diodes (OLEDs) are widely used in display technology and are also being investigated for lighting applications. A comprehensive understanding of these devices is therefore important if their properties are to be harnessed to their full potential. Researchers from the University of Tsukuba have directly observed the photoexcited electron dynamics in an organic film using time-resolved photoelectron emission microscopy. Their findings are published in Advanced Optical Materials .

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18.06.2021
10:53 AzoNano.com Park FX40 - A New Class of Atomic Force Microscope

A New Class of Atomic Force Microscope is coming. Park FX40 will launch on June 25, 2021 Learn more at https://parksystems.com/fx #FX40 #ThenewclassofAFM #ParkSystems Park Systems developed the...

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16.06.2021
18:07 Nature.Com Localization atomic force microscopy

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01.06.2021
21:00 Aps.org Editors' Suggestions Inducing ferroelastic domains in single-crystal ${\mathrm{CsPbBr}}_{3}$ perovskite nanowires using atomic force microscopy

Author(s): Lucas A. B. Marçal, Sandra Benter, Austin Irish, Dmitry Dzhigaev, Eitan Oksenberg, Amnon Rothman, Ella Sanders, Susanna Hammarberg, Zhaojun Zhang, Simone Sala, Alexander Björling, Eva Unger, Anders Mikkelsen, Ernesto Joselevich, Rainer Timm, and Jesper WallentinUnderstanding and controlling the formation and dynamics of ferroelastic domains can be key to enhance metal halide perovskite device performance, but established methods lack spatial control at the level of single domains. Here, the authors induced the formation of ferroelastic domains in CsPbBr 3 nanowires using an atomic force microscope tip, and studied the structural changes using nanofocused x-ray diffraction with a 60-nm beam. The applied stress locally induced

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25.05.2021
16:43 Nanowerk.com Researchers discover new method of seeing graphene growing using a standard electron microscope

Researchers have revealed a new method that enables common laboratory scanning electron microscopes to see graphene growing over a microchip surface in real time.

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24.05.2021
16:22 AzoNano.com New Method Enables Scanning Electron Microscopes to See Graphene Growing in Real Time

Researchers from the University of Surrey have revealed a new method that enables common laboratory scanning electron microscopes to see graphene growing over a microchip surface in real time. This...

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21.05.2021
16:57 Phys.org New method for observes graphene growing using standard electron microscope

Researchers from the University of Surrey have revealed a new method that enables common laboratory scanning electron microscopes to see graphene growing over a microchip surface in real time.

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30.04.2021
13:57 AzoNano.com New Cypher VRS1250 Video-Rate Atomic Force Microscope Enables True Video-Rate Imaging at up to 45 Frames per Second

April 27, 2021 (Santa Barbara, CA) Oxford Instruments Asylum Research today announced the launch of the new Cypher VRS1250 video-rate atomic force microscope (AFM).   (Left) The Cypher...

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23.04.2021
17:20 Phys.org Using a new kind of electron microscopy to measure weak van der Waals interactions

A team of researchers from China, the Netherland and Saudi Arabia has used a new kind of electron microscopy to measure weak van der Waals interactions. In their paper published in the journal Nature, the group describes creating what they describe as a molecular compass to measure weak van der Waals interactions using a new type of electron microscopy developed in the Netherlands.

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22.04.2021
15:33 Phys.org First atomic model of human telomerase constructed by electron cryo-microscopy

Telomeres are large nucleoproteins structures that cap the ends of chromosomes in eukaryotic cells. When a cell divides, a small portion of the telomere is lost due to the inherently incomplete process of genome replication. If left unchecked, over time the telomeres will reach a critically short length and the cell will face genomic instability, deterioration or death. To offset this shortening, an essential enzyme called telomerase rebuilds the telomeres by synthesizing new telomeric DNA repeats at chromosome ends. Kelly Nguyen's group, in the LMB's Structural Studies Division, has solved the first complete atomic model of this enzyme and discovered a histone dimer as novel telomerase subunits.

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21.04.2021
19:25 AzoNano.com Park Systems, World Leading Atomic Force Microscopy Manufacturer Hits 1 Trillion KRW Mark at KOSDAQ

Park Systems, world leading manufacturer of Atomic Force Microscopes announced the company stock valuation exceeded 1 Trillion KRW (almost $1 Billion USD) at the end of KOSDAQ on...

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14.04.2021
18:57 Aps.org Editors' Suggestions Understanding Complex Magnetic Spin Textures with Simulation-Assisted Lorentz Transmission Electron Microscopy

Author(s): Arthur R.C. McCray, Timothy Cote, Yue Li, Amanda K. Petford-Long, and Charudatta PhatakLorentz transmission electron microscopy (LTEM) is frequently used to image magnetic induction maps of topological magnetic spin structures. These induction maps are visually intuitive, but can be misinterpreted for materials in which the magnetization differs greatly from the integrated induction, leading to ambiguous determination of spin structures. The authors present PyLorentz, their open-source software for simulating LTEM images from three-dimensional micromagnetic simulations. By applying the technique to Néel skyrmions, they demonstrate that combining simulated and experimental LTEM images gives a more complete picture of complex spin structures. [Phys. Rev. Applied 15, 044025] Published Wed Apr 14, 2021

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08.04.2021
11:23 Technology.org Research Snapshot: New microscopy technique of electron distributions and theory unveils a feature that can shape applications of a class of quantum materials

A team of researchers led by Oak Ridge National Laboratory microscopist Miaofang Chi and Vanderbilt theoretical physicist Sokrates Pantelides has used

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